{"id":4959,"date":"2022-03-02T09:51:09","date_gmt":"2022-03-02T08:51:09","guid":{"rendered":"https:\/\/www.iadchem.uam.es\/?p=4959"},"modified":"2022-03-28T11:11:21","modified_gmt":"2022-03-28T09:11:21","slug":"self-assembled-netallacages-a-new-generation-of-targeted-drug-delivery-systems-and-theranostic-agents","status":"publish","type":"post","link":"https:\/\/www.iadchem.uam.es\/?p=4959","title":{"rendered":"Self-assembled Metallacages: A New Generation of Targeted Drug Delivery Systems and Theranostic Agents"},"content":{"rendered":"<p><a href=\"https:\/\/www.iadchem.uam.es\/wp-content\/uploads\/2022\/03\/casini_angela_featured.jpg\"><img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone wp-image-5018 size-full\" src=\"https:\/\/www.iadchem.uam.es\/wp-content\/uploads\/2022\/03\/casini_angela_featured.jpg\" alt=\"Angela Casini\" width=\"840\" height=\"450\" srcset=\"https:\/\/www.iadchem.uam.es\/wp-content\/uploads\/2022\/03\/casini_angela_featured.jpg 840w, https:\/\/www.iadchem.uam.es\/wp-content\/uploads\/2022\/03\/casini_angela_featured-300x161.jpg 300w, https:\/\/www.iadchem.uam.es\/wp-content\/uploads\/2022\/03\/casini_angela_featured-768x411.jpg 768w\" sizes=\"(max-width: 840px) 100vw, 840px\" \/><\/a><\/p>\n<p style=\"text-align: center;\"><span style=\"color: #808080;\"><em><span style=\"text-align: center;\">Prof. Angela Casini<\/span><\/em><\/span><\/p>\n<p style=\"text-align: justify;\"><strong>Title:<\/strong> Self-assembled Metallacages: a new generation of targeted drug delivery systems and theranostic agents.<br \/>\n<strong>When:<\/strong> 15:00 CET, Wednesday, March 30<sup>th<\/sup>, 2022.<br \/>\n<strong>Place:<\/strong> Conference Hall, Module 0, Faculty of Sciences, Universidad Aut\u00f3noma de Madrid.<br \/>\n<strong>Speaker:<\/strong> Prof. Angela Casini from the Technical University of Munich, Germany.<\/p>\n<p style=\"text-align: justify;\"><span class=\"dropcap\">T<\/span>he biomedical application of discrete supramolecular metal-based complexes, specifically self-assembled 3D-metallacages, is an emergent field of study.\u00a0The robustness and modular composition of such supramolecular metal-based structures allows for the incorporation of different functionalities in the same scaffold to enable imaging in cells via different modalities, but also active tumor targeting and stimuli-responsiveness. Thus, metallacages may constitute ideal scaffolds to develop multimodal theranostic agents. Of note, the host-guest\u00a0chemistry of metallacages can also be exploited to design novel targeted drug delivery systems for anticancer chemotherapeutics and radioactive imaging agents.<\/p>\n<p style=\"text-align: justify;\">In this lecture the pivotal concepts in this fascinating research area will be summarized, starting with the main synthetic and design principles and illustrating representative examples of palladium(II)-based cages from our group. Certainly, the myriad of possible metallacage-structures and their almost limitless modularity and tunability suggest that the biomedical applications of such complex chemical entities will continue along this already promising path.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prof. Angela Casini Title: Self-assembled Metallacages: a new generation of targeted drug delivery systems and theranostic agents. When: 15:00 CET, Wednesday, March 30th, 2022. Place: Conference Hall, Module 0, Faculty of Sciences, Universidad Aut\u00f3noma de Madrid. Speaker: Prof. Angela Casini from the Technical University of Munich, Germany. The biomedical application of discrete supramolecular metal-based complexes,&hellip;<\/p>\n","protected":false},"author":3,"featured_media":5018,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[70],"tags":[167,160],"class_list":["post-4959","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lectures","tag-drug-delivery","tag-metallacages","entry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Self-assembled Metallacages: A New Generation of Targeted Drug Delivery Systems and Theranostic Agents - IAdChem - Institute for Advanced Research in Chemical Sciences<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.iadchem.uam.es\/?p=4959\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Self-assembled Metallacages: A New Generation of Targeted Drug Delivery Systems and Theranostic Agents - IAdChem - Institute for Advanced Research in Chemical Sciences\" \/>\n<meta property=\"og:description\" content=\"Prof. Angela Casini Title: Self-assembled Metallacages: a new generation of targeted drug delivery systems and theranostic agents. When: 15:00 CET, Wednesday, March 30th, 2022. Place: Conference Hall, Module 0, Faculty of Sciences, Universidad Aut\u00f3noma de Madrid. Speaker: Prof. Angela Casini from the Technical University of Munich, Germany. The biomedical application of discrete supramolecular metal-based complexes,&hellip;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.iadchem.uam.es\/?p=4959\" \/>\n<meta property=\"og:site_name\" content=\"IAdChem - Institute for Advanced Research in Chemical Sciences\" \/>\n<meta property=\"article:published_time\" content=\"2022-03-02T08:51:09+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-03-28T09:11:21+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.iadchem.uam.es\/wp-content\/uploads\/2022\/03\/casini_angela_featured.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"840\" \/>\n\t<meta property=\"og:image:height\" content=\"450\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"IADCHEM Editor\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"IADCHEM Editor\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.iadchem.uam.es\\\/?p=4959#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.iadchem.uam.es\\\/?p=4959\"},\"author\":{\"name\":\"IADCHEM Editor\",\"@id\":\"https:\\\/\\\/www.iadchem.uam.es\\\/#\\\/schema\\\/person\\\/acff178c6fdfa63f2a2f3082da68abf2\"},\"headline\":\"Self-assembled Metallacages: A New Generation of Targeted Drug Delivery Systems and Theranostic Agents\",\"datePublished\":\"2022-03-02T08:51:09+00:00\",\"dateModified\":\"2022-03-28T09:11:21+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.iadchem.uam.es\\\/?p=4959\"},\"wordCount\":211,\"image\":{\"@id\":\"https:\\\/\\\/www.iadchem.uam.es\\\/?p=4959#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.iadchem.uam.es\\\/wp-content\\\/uploads\\\/2022\\\/03\\\/casini_angela_featured.jpg\",\"keywords\":[\"Drug delivery\",\"Metallacages\"],\"articleSection\":[\"Lectures\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.iadchem.uam.es\\\/?p=4959\",\"url\":\"https:\\\/\\\/www.iadchem.uam.es\\\/?p=4959\",\"name\":\"Self-assembled Metallacages: A New Generation of Targeted Drug Delivery Systems and Theranostic Agents - 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